Patrick Dennis, orphaned in 1928 when his father Edwin dies unexpectedly, is placed in the care of his aunt Mame Dennis in Manhattan. Mame is flamboyant and exuberant, hosting frequent parties with a variety of guests and free-spirited friends Mr. Babcock (Fred Clark), Patrick's assigned executor, objects to Mame's unconventional way of living and tries to force her to send Patrick to prep school. As Mame and Patrick grow closer, Mr. Babcock tries to discipline Patrick and threatens to separate the two if Mame does not comply with his wishes.