Sister, Sister is an American television sitcom starring identical twins Tia and Tamera Mowry. It premiered on April 1, 1994, and concluded on May 23, 1999 after six seasons. The premise was that Tia Landry and Tamera Campbell were separated at birth and one was adopted by a single mother while the other was adopted by a couple, although the mother died afterwards; 14 years later the two accidentally found each other and reunited.